Panorama next generation nipt
Natera Panorama Test
Product Description
The Natera Panorama NIPT Test is a prenatal DNA screening blood test. It provides you with information about the likelihood that your baby has certain genetic conditions based on a maternal blood sample (a simple blood test from mum-to-be). Non-invasive prenatal testing (NIPT) uses this blood sample from the mother to analyse DNA from the placenta (afterbirth) for certain chromosome conditions such as Down Syndrome, Patau Syndrome and Edward Syndrome that could affect a baby’s health.
Non-invasive prenatal screening can be helpful in learning more about your baby’s health. It can help you to consider all of your options, how to manage your pregnancy and consider if special management or care is needed. Non-invasive prenatal screening is safe and usually involves just a simple blood test. Your results are usually available about 2 weeks after the test. We advise all parents-to-be to learn about prenatal screening before undertaking any test and it is vital that your results are properly communicated and explained.
Here at Innermost Healthcare, our NIPT Panorama Test from Natera includes:
• the opportunity to discuss prenatal
Test Comments: Help
For singleton pregnancies: Panorama® is a screening test for common aneuploidies (trisomy 13, trisomy 18, trisomy 21, sex chromosome aneuploidy, triploidy and 22q11.2). By utilizing SNPs and unique bioinformatics to differentiate between the maternal and fetal genotype, Panorama has high sensitivity and specificity in the NIPT industry for these conditions. …For singleton pregnancies: Panorama® is a screening test for common aneuploidies (trisomy 13, trisomy 18, trisomy 21, sex chromosome aneuploidy, triploidy and 22q11.2). By utilizing SNPs and unique bioinformatics to differentiate between the maternal and fetal genotype, Panorama has high sensitivity and specificity in the NIPT industry for these conditions. When ordering, be advised that screening for 22q11.2 deletion syndrome is automatically run with Panorama unless the provider “opts out”. Panorama’s Extended panel includes screening for these additional microdeletion syndromes: Prader Willi syndrome, Angelman syndrome, Cri du Chat syndrome, and 1p36 deletion syndrome. For monozygotic twin pregnancies: Panorama® is a screening test for common aneuploidies (trisomy 13, trisomy 18, trisomy 21, sex chrom
What Panorama Screens For
Panorama is the only non-invasive prenatal screening examine that distinguishes between fetal and maternal cell-free DNA thanks to SNP-based sequencing and Natera’s proprietary algorithm. Using advanced bioinformatics techniques, Panorama screens for a broad panel of chromosomal conditions, including:
Chromosome Conditions
Sex Chromosome Conditions
Microdeletions
In Twin Pregnancies
Non-identical or fraternal twins
If our reviewing finds that your twins are identical, Panorama can additionally screen for:
Egg Donor or Surrogate Pregnancies
Information about the Test
What does the DETECTION RATE mean?
The detection rate or sensitivity is the ability to correctly identify a neonate with a specific condition. For example, in a group of babies with Trisomy 21, Panorama will correctly identify more than 99% of those cases.
What is SPECIFICITY?
This is the ability to correctly identify a baby that does not have the condition.
What is the POSITIVE PREDICTIVE VALUE (PPV)?
This is the likelihood that if the result says lofty probability that the fetus will actually have the condition.
- If Panorama Test shows a high probability of Tri
If you have product-related questions about the Panorama™ prenatal screen, you can schedule a complimentary 15 minute genetic information session with one of our board-certified genetic counselors or call 844-778-4700.
If you have billing related questions, you can speak to one of the Natera representatives at 877-869-3052 (select 2 to speak with one of our billing experts) between 7am and 7pm CST, Monday through Friday. Except major holidays. Email insbilling@natera.com for assistance outside of business hours.
If you have personal healthcare related questions (i.e., family history, ultrasound finding, healthcare decision making…etc) or would like to take the Panorama™ prenatal screen, we encourage you to speak to your healthcare provider.
If you have any other questions, you can speak to a Natera representative at call 844-778-4700 between 7am and 7pm CST, Monday through Friday, 9am to 5pm CST Saturday. Except major holidays.
Trisomy 21 (Down syndrome)
Babies with Down syndrome have three copies of chromosome 21 and have intellectual disabilities that range from mild to severe. Children with Down syndrome will need extra medical care depending on the child’s specific health problems. Early intervention has allowed many individuals with Down syndrome to lead healthy and productive lives. The presence of medical conditions, like heart defects, can affect the lifespan in these children and adults; however, most individuals with Down syndrome will live into their 60s. Miscarriage occurs in about 30% of pregnancies with Down syndrome while overall about 1 in 700 babies are born with Down syndrome.
Trisomy 18 (Edwards syndrome)
Babies with trisomy 18 have three copies of chromosome 18 and have severe intellectual disabilities and birth defects typically involving the heart, brain, and kidneys. Babies with trisomy 18 can also have visible birth defects such as an opening in the lip (cleft lip) with or without an opening in the roof of the mouth (cleft palate), a small head, clubbed feet, underdeveloped fingers, and toes, and a small jaw. Unfortunately, most pregnancies with trisomy 18 will miscarry